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PLASMINOGEN ACTIVATOR INHIBITOR-2

[[Image:|px|Plasminogen activator inhibitor-2 chemical structure]]
serpin peptidase inhibitor, clade B (ovalbumin), member 2
Identifiers
Symbol(s) SERPINB2 PLANH2, PAI2
Entrez 5055
OMIM 173390
RefSeq NM_002575
UniProt P05120
PDB [1]
Other data
EC number [2]
Locus Chr. 18 q21.3

Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor which inactivates tPA & urokinase. It is only present in relevant quantities during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy.

See also

External links

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Coagulation
Coagulation factors: - Fibrin (I) - (Pro)thrombin (II) - FV - FVII - FVIII - FIX - FX - FXI - FXII - FXIII - HMWK - vWF - Tissue factor
Inhibitors: Antithrombin - Protein C - Protein S - Protein Z - ZPI - TFPI
Fibrinolysis: Plasmin - tPA/urokinase - PAI-1/2 - α2-AP - TAFI